Bacterial Isolate Genome Sequencing

End-to-end whole genome sequencing (WGS) and analysis of microbial isolates

Cmbio offers end-to-end whole genome sequencing (WGS) and analysis of microbial isolates. DNA Extraction, Library preparation and Next-Generation Sequencing (NGS) is carried out in our CLIA-certified facilities. For data interpretation we use an in-house bioinformatics platform that is built around Cmbio’s class-leading databases and has been optimized for isolate whole genome data.

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Is Bacterial Whole-Genome Sequencing right for you?

WGS of bacterial isolates offers unique advantages over traditional typing methods and is now available at very affordable rates. Unlike PCR, this affordable technology reveals the complete genetic makeup of an organism and offers unprecedented insight. A single assay reveals:

Unambiguous taxonomic classification
Highly accurate depiction of strain relatedness, pathogenesis and transmission
Functional characteristics like antimicrobial resistance, virulence, and metabolic capabilities

Flexible timelines

Our team will provide regular updates on your project's status klyn.

CLIA-certified & GCP-compliant

facilities is equipped to handle samples from around the globe

Experts

A team of over 100 experts in microbiology, bioinformatics, metabolomics & more.

Multiple sample types

Experience in 20+ sample types. Human, Environmental, food & more

What type of analysis is included?

Raw data via AWS Transfer
Data QC, Genome Assembly, Strain ID, SNP Analysis & Phylogenetic Trees
Cmbio Analysis Report
Data consultation & walk-through
Characterization – AMR, Virulence, MLST, Average Nucleotide Identity & Functional Annotation
Custom Bioinformatics available on request

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Our standard package

Whenever you sequence your strains with us, we always provide the following:

Optional pre- and post-project meetings with a specialist
DNA extraction and library preparation
Sequencing
Pre- and post-sequencing quality control
De novo assembly
Taxonomic profiling
Gene annotation
Access to raw data, result files, and a detailed project report

What common applications are there for isolate sequencing & analysis?
How long will the process take?
Do you have the ability to sequence and analyze any species?
Bacterial and fungal organisms differ tremendously based on their cell wall thickness, genome size & GC content. As such, some organisms require a slightly more specialized approach when it comes to DNA extraction, library preparation techniques, targeted coverage and analysis strategy. Once we receive a list of your organisms of interest, we’ll assess these nuances and get back to you with a proposed plan of action. Nonetheless, by assembling genomes de novo, this is well suited to novel strain discovery in a wide range of applications.